Mass Spectrometry

Spectroscopy tools in Nanotechnology

Nanoscale liquid chromatography coupled to tandem mass spectrometry has become an indispensable tool in the field of proteomics now-a-days. The advantages are grabbed with the sensitivity of nanotechnology over conventional LC-MS that allow the analysis of various  peptide mixtures in limited situations. This approach gives a strong cation-exchange, sample enrichment, reversed-phase chromatography and nanospray ion trap mass spectroscopy with data dependent tandem mass spectrometry spectra acquisition. Nanocolumn liquid chromatography and largely synonymous capillary liquid chromatography (capillary LC) are the most recent results of this process where miniaturization of column dimensions and sorbent particle size play crucial role along with the advances in mass spectrometry that has really brought a breakthrough. Configuration of Nano LC-electrospray ionization mass spectrometry (LC-ESI-MS) has become a essential tool in bioanalytical chemistry that basically indulges in proteomics. This particular session includes the brief account on pharmaceutical and biomedical research, Nano-proteomic analysis and Nano-proteomic analysis.